RAF Typhoon FGR4s have operated alongside French aircraft in a joint strike against an underground arms cache in Syria employed by the Daesh militant organization, as stated by the UK's MoD.
The facility, located using reconnaissance, was assessed as containing munitions and bombs, the release indicated, and was located in mountains just to the north of Palmyra in the heart of Syria.
"The RAF jets used precision-guided Paveway IV munitions to hit a series of access tunnels leading to the site... initial indications indicate the target was engaged successfully," officials stated.
There was no sign of any civilian casualties in the strike on Saturday evening and every plane involved returned to base without incident, the ministry further stated.
The Typhoon FGR4s were assisted by a Voyager refuelling tanker.
The Islamic State group - referred to as ISIS - established jihadist rule over large swathes of both Syria and Iraq prior to its 2019 collapse.
"This action underscores British leadership, and resolve to work closely with allied nations, to stamp out any re-emergence of Daesh and their harmful and extremist ideologies in the area," UK Defence Secretary John Healey stated.
UK warplanes have conducted patrols over Syrian airspace to "deter any attempted resurgence" of the group following its routing at the climactic battle in Baghuz in 2019, the MoD reported.
"I extend gratitude to all the members of the UK armed forces who took part in this strike for their professionalism and their bravery," Healey said. "They were among numerous British personnel stationed over Christmas and New Year. This operation, to remove militants who endanger our security, shows how UK forces are ready to step up, all year round, keeping Britain secure domestically and influential overseas."
In December, the US military conducted what it called a "large-scale strike" targeting Islamic State objectives in the country, after an attack killed two US servicemembers and a civilian linguist in the Palmyra area.
The U.N. estimates IS still has an estimated 5,000 to 7,000 combatants in Syria and Iraq.